Omeprazole Injection is used to treat Peptic ulcer, H. pylori infection, Gastro-oesophageal reflux disease, Zollinger-Ellison syndrome, Oesophagitis, Acid-related dyspepsia, NSAID-associated ulceration
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It's advised to be cautious when consuming alcohol with Xelopes. Consult your doctor.
Xelopes 40mg Injection may be unsafe during pregnancy. Your doctor will assess the benefits and risks before prescribing it.
Xelopes 40mg Injection is likely unsafe during breastfeeding. Consult your doctor for advice.
It's unknown if Xelopes 40mg Injection affects driving ability. Avoid driving if you experience concentration or reaction issues.
Xelopes 40mg Injection is safe for patients with kidney disease without dose adjustment.
Use Xelopes 40mg Injection with caution in severe liver disease. Dose adjustment may be necessary. Consult your doctor, especially for long-term use.
It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
While generally well-tolerated, Xelopes may cause mild and reversible side effects like skin rash, diarrhea, headache, and gastrointestinal reactions. Rare but serious adverse effects include liver enzyme increases, hepatitis, and anaphylactic shock.
Xelopes is prescribed for various conditions, including gastric and duodenal ulcers, NSAID-associated ulcers, gastroesophageal reflux disease, acid-related dyspepsia, severe ulcerating reflux esophagitis, prophylaxis of acid aspiration during anesthesia, Zollinger-Ellison syndrome, and Helicobacter pylori-induced peptic ulcers.
Its active ingredient, omeprazole, inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme system in gastric parietal cells. This effect begins within an hour of oral administration, peaks within two hours, and lasts up to 72 hours. When discontinued, gastric acid secretion gradually returns over 3 to 5 days.
Adult Dose:
Intravenous Dose:
Child Dose:
Renal Dose: No dosage adjustment is needed for renal impairment.
Xelopes can be administered orally or via intravenous injection or infusion, depending on the patient's needs and circumstances.
It's important to consider potential interactions with other medications, such as ketoconazole, diazepam, phenytoin, warfarin, and clarithromycin, among others. For instance, co-administration with clopidogrel should be avoided due to reduced pharmacological activity.
Omeprazole is contraindicated in patients with known hypersensitivity to it.
Pregnant and breastfeeding women should consult their healthcare provider before using Xelopes.
Before starting treatment with omeprazole, it's crucial to exclude the possibility of gastric malignancy. This medication is not recommended during pregnancy, lactation, or for children under one year old. Monitoring magnesium concentrations is advised before starting treatment and periodically thereafter. While limited data suggest omeprazole may be present in breast milk, there's a lack of clinical data on its effects on breastfed infants or milk production. It's essential to weigh the developmental and health benefits of breastfeeding against the mother's clinical need for therapy and any potential adverse effects on the infant from treatment or the mother's underlying condition.
It's also important to store Xelopes in a dry place away from light and heat, out of the reach of children.
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